| Izina ry'ikirango | ActiTide-AH3 |
| URUBANZA No. | 616204-22-9 |
| INCI Izina | Acetyl Hexapeptide-3 |
| Imiterere yimiti |  |
| Gusaba | Amavuta yo kwisiga, serumu, mask, koza mumaso |
| Amapaki | Urushundura 1kg kuri icupa / 20kgs net kuri buri ngoma |
| Kugaragara | Amazi / Ifu |
| Acetyl hexapeptide-3 (8) (Amazi) | 450-550ppm 900-1200ppm |
| Isuku (Ifu) | 95% min |
| Gukemura | Amazi ashonga |
| Imikorere | Urutonde rwa peptide |
| Ubuzima bwa Shelf | Imyaka 2 |
| Ububiko | Ubike ahantu hakonje kandi humye, kure yumucyo. 2 ~ 8℃kubika. |
| Umubare | 2000-5000ppm |
Gusaba
Kurwanya inkari hexapeptide ActiTide-AH3 yerekana kuvumbura ibintu byiza bishingiye ku nzira ya siyansi kuva ku gishushanyo mbonera kugera ku musaruro wa GMP. Ubushakashatsi bwibanze bwibanze bwibinyabuzima bwibikorwa byo kurwanya inkari byatumye iyi hexapeptide yimpinduramatwara yatwaye isi yo kwisiga.
Hanyuma, kuvura inkeke bishobora guhangana nubushobozi bwa Botulineum Toxin A ariko igasiga kuruhande ingaruka, inshinge nigiciro kinini: ActiTide-AH3.
Inyungu zo kwisiga:
ActiTide-AH3 igabanya ubujyakuzimu bw'iminkanyari iterwa no kugabanuka kw'imitsi yo mu maso, cyane cyane mu gahanga no mu maso.
Nigute ActiTide-AH3 ikora?
Imitsi yandura iyo yakiriye neurotransmitter igenda muri vicle. Uruganda rwa SNARE (SNAp RE ceptor) ni ngombwa kuri uku gusohora kwa neurotransmitter kuri synapsis (A. Ferrer Montiel et al, Ikinyamakuru cya Biologiya Chemistry, 1997, 272, 2634-2638). Nibintu bitatu byakozwe na poroteyine VAMP, Syntaxin na SNAP-25. Uru ruganda rumeze nkururondogoro rufata imitsi ikayihuza na membrane kugirango irekure neurotransmitter.
ActiTide-AH3 nigana impera ya N-terminal ya SNAP-25 irushanwa na SNAP-25 kumwanya uri murwego rwa SNARE, bityo bigahindura imiterere yabyo. Niba urwego rwa SNARE rudahungabana gato, imitsi ntishobora guhagarara no kurekura neurotransmitter neza bityo rero imitsi ikagabanuka, bikabuza gushiraho imirongo n'iminkanyari.
ActiTide-AH3 ni umutekano, uhendutse, kandi woroshye kuri Botulinum Toxin, yibanda cyane kuburyo bumwe bwo gukora iminkanyari muburyo butandukanye cyane.
