| Izina ry'ikirango | ActiTide-AH3 |
| URUBANZA No. | 616204-22-9 |
| INCI Izina | Acetyl Hexapeptide-8 |
| Gusaba | Amavuta, Serumu, Mask, Isuku yo mumaso |
| Amapaki | 100g / icupa, 1kg / igikapu |
| Kugaragara | Ifu yera-yera |
| Gukemura | Amazi ashonga |
| Imikorere | Urutonde rwa peptide |
| Ubuzima bwa Shelf | Imyaka 2 |
| Ububiko | Bika kontineri ifunze cyane ahantu hakonje, humye kuri 2 - 8 ° C. |
| Umubare | 0.005-0.05% |
Gusaba
Ubushakashatsi bwakozwe muburyo bwo kurwanya inkeke bwatumye havumburwa ActiTide-AH3, hexapeptide idasanzwe yakozwe hifashishijwe uburyo bwa siyanse kuva mubishushanyo mbonera kugeza ku musaruro wa GMP, hamwe nibisubizo byiza.
ActiTide-AH3 itanga imbaraga zo kugabanya iminkanyari ugereranije na Botulineum Toxin Ubwoko A, mugihe wirinze ingaruka zo gutera inshinge no gutanga ikiguzi kinini.
Inyungu zo kwisiga:
ActiTide-AH3 igabanya ubujyakuzimu buterwa no kugabanuka kw'imitsi yo mu maso, hamwe n'ingaruka zigaragara ku gahanga no mu mitsi.
Uburyo bwibikorwa:
Kugabanuka kw'imitsi bibaho kuri neurotransmitter kurekura imitsi ya synaptic. Uruganda rwa SNARE - iteraniro rya gatatu rya poroteyine za VAMP, Syntaxin, na SNAP-25 - ni ngombwa mu guhagarika imitsi na neurotransmitter exocytose (A. Ferrer Montiel et al., JBC 1997, 272: 2634-2638). Uru ruganda rukora nkibikoresho bya selile, gufata imitsi no gutwara membrane fusion.
Nukwigana imiterere ya SNAP-25 N-terminus, ActiTide-AH3 irushanwa na SNAP-25 kugirango yinjizwe muri SNARE, ihindura inteko yayo. Guhungabanya ikigo cya SNARE byangiza imiyoboro ya vicle no kurekurwa kwa neurotransmitter, bigatuma kugabanuka kwimitsi no kwirinda iminkanyari no kumurongo mwiza.
ActiTide-AH3 nuburyo bwizewe, bwubukungu, kandi bworoheje bwubwoko bwa Botulinum Toxin Ubwoko A. Bwibanze cyane kumayira amwe yo gukora iminkanyari ariko ikora muburyo butandukanye.
