| Izina ry'ikirango | ActiTide™ AH3 (Ifite amazi 1000) |
| Nimero ya CAS | 616204-22-9; 56-81-5; 107-88-0; 7732-18-5; 99-93-4; 6920-22-5 |
| Izina rya INCI | Asetili Hexapeptide-8; Gliserini; Butylene Glycol; Amazi; Hydroxyacetophenone; 1,2-Hexanediol |
| Porogaramu | Amavuta yo kwisiga, Seramu, Maske, Isukura mu maso |
| Pake | 1kg/icupa |
| Isura | Amazi abonerana kandi asobanutse afite impumuro idasanzwe |
| Gushonga | Amazi ashongeshwa |
| Imikorere | Uruhererekane rwa Peptide |
| Igihe cyo kubika | Imyaka 2 |
| Ububiko | Bika ikintu gifunze neza ahantu hakonje kandi humutse kuri 2 - 8°C. |
| Igipimo | 3.0-10.0% |
Porogaramu
Ubushakashatsi ku buryo bw'ibanze bwo kurwanya iminkanyari bwatumye havumburwa ActiTide™ AH3, hexapeptide nshya yakozwe binyuze mu buryo bwa siyansi kuva ku gushushanya neza kugeza ku gukora GMP, kandi byatanze umusaruro mwiza.
ActiTide™ AH3 itanga ubushobozi bwo kugabanya iminkanyari nk'ubwa Botulinum Toxin Type A, mu gihe yirinda ibyago byo guterwa inshinge kandi igatanga uburyo bwo kugabanya iminkanyari.
Ibyiza byo kwisiga:
ActiTide™ AH3 igabanya ubujyakuzimu bw'iminkanyari buterwa no kubyimba kw'imitsi yo mu maso, bikagira ingaruka zikomeye ku gahanga no ku minkanyari yo mu maso.
Uburyo bwo gukora:
Imitsi irakomera iyo neurotransmitter ivuye muri synaptic vesicles. SNARE complex - ihuriro rya ternary rya VAMP, Syntaxin, na SNAP-25 proteins - ni ingenzi mu gufunga vesicle na neurotransmitter exocytosis (A. Ferrer Montiel et al., JBC 1997, 272:2634-2638). Iyi complex ikora nk'aho ifata selile, igafata vesicles kandi igatera membrane fusion.
Nk'uburyo bwo kwigana imiterere ya SNAP-25 N-terminus, ActiTide™ AH3 ihangana na SNAP-25 kugira ngo yinjizwe muri SNARE complex, bigatuma ihinduka. Guhagarika complex ya SNARE bibangamira ubwikorezi bw'imitsi no kurekura kwa neurotransmitter, bigatuma imitsi igabanuka kandi ikarinda iminkanyari no kurema imirongo mito.
ActiTide™ AH3 ni uburyo bwizewe, buhendutse kandi bworoshye bwo gusimbura Botulinum Toxin Type A. Ireba mu buryo bumwe bwo kurema iminkanyari ariko ikora mu buryo butandukanye.
