| Izina ry'ikirango: | Recombinant PDRN |
| CAS No.: | / |
| INCI Izina: | ADN ya Sodium |
| Porogaramu: | Amavuta yo kwisiga yo hagati-yohejuru, amavuta yo kwisiga, amavuta, amaso, masike, nibindi |
| Ipaki: | 50g |
| Kugaragara: | Ifu yera |
| Igipimo cy'ibicuruzwa: | Urwego rwo kwisiga |
| Gukemura: | Gushonga mumazi |
| pH (igisubizo cyamazi 1%): | 5.0 -9.0 |
| Igihe cyo kubika | Imyaka 2 |
| Ububiko: | Bika ahantu hakonje kure yizuba ryubushyuhe bwicyumba |
| Umubare: | 0.01% -2.0% |
Gusaba
R&D Amavu n'amavuko:
Gakondo PDRN ikurwa cyane cyane muri salmon testicular tissue. Bitewe nuburyo butandukanye mubuhanga bwa tekiniki mubakora, inzira ntabwo ihenze kandi idahindagurika gusa ahubwo iranagerageza kwemeza ibicuruzwa byera kandi bigahinduka. Byongeye kandi, kwishingikiriza cyane ku mutungo kamere bitera igitutu kinini ku bidukikije kandi bikananirwa guhaza isoko rikenewe ku isoko.
Synthesis ya salmon ikomoka kuri PDRN ikoresheje inzira ya biotechnologie irenga neza imipaka yo gukuramo ibinyabuzima. Ubu buryo ntabwo bwongera umusaruro gusa ahubwo binakuraho gushingira kumutungo kamere. Ikemura ihindagurika ryiza riterwa n’umwanda cyangwa umwanda mugihe cyo kuyikuramo, kugera ku ntera isimbuka mu kweza ibice, guhuza ibikorwa, no kugenzura umusaruro, bityo bigatuma inganda zihamye kandi nini.
Ibyiza bya tekiniki:
1. 100% Byakozwe neza Urutonde rwimikorere
Ikora neza uko urutonde rw'ibintu rugenda rukorwa, igakora ibikoresho bya aside nucleic byihariye "byakozwe neza".
2. Ibipimo bya molekulari bihoraho hamwe nuburinganire bwimiterere
Kugenzura ibice by'uburebure hamwe nuburyo bukurikirana byongera cyane molekuline ibice bya homogeneity hamwe na transdermal imikorere.
3. Ibice bidakomoka ku nyamaswa, bihuye n'amahame mpuzamahanga agenga
Yongera kwemerwa kwisoko mubice byoroshye byo gusaba.
4. Ubushobozi burambye kandi bunini ku musaruro wisi yose.
Yigenga ku mutungo kamere, ituma ubunini butagira imipaka hamwe n’isoko rihamye ku isi binyuze mu buryo bwo gusembura no kweza, bikemura mu buryo bwuzuye ibibazo bitatu by’ingenzi bya PDRN gakondo: ibiciro, urunigi rutangwa, hamwe n’ibidukikije.
Recombinant PDRN ibikoresho fatizo bihuza neza nicyatsi kibisi kandi kirambye gikenewe cyiterambere hagati-hejuru-yohejuru.
Ingaruka namakuru yumutekano:
1. Guteza imbere cyane Gusana no Kuvugurura:
Igerageza ryakozwe muri vitro ryerekanye ko uyu muti wongera cyane ubushobozi bwo kwimuka kw'uturemangingo, ugaragaza imikorere myiza cyane mu guteza imbere ikorwa rya collagen ugereranije na PDRN isanzwe, kandi utanga ingaruka nziza zo kurwanya iminkanyari no gukomeza.
2. Ingaruka zo Kurwanya Indurwe:
Irabuza neza kurekura ibintu byingenzi bitera (urugero, TNF-α, IL-6).
3. Ubushobozi budasanzwe bwo guhuza imbaraga:
Iyo uhujwe na sodium hyaluronate (kwibanda: 50 μg / mL buri umwe), igipimo cyimuka cyimuka gishobora kwiyongera kugera kuri 93% mugihe cyamasaha 24, byerekana ubushobozi bwiza bwo guhuza porogaramu.
4. Urwego rwo kwibanda ku mutekano:
Mu bushakashatsi bwa vitro bwerekana ko 100-200 μg / mL ari ahantu hose hizewe kandi hafite imbaraga zo guhuriza hamwe, kuringaniza byombi bikwirakwiza (ingaruka zamasaha 48-72) nibikorwa byo kurwanya inflammatory.
5. Kuzamura Igisekuru cya Kolagen:
Recombinant PDRN yerekanye ubwiyongere bwikubye 1.5 mubwoko bwa I kolagen ugereranije nitsinda rishinzwe kugenzura ubusa, mugihe kandi herekana ubwiyongere bwikubye 1,1 mubwoko bwa III bwa kolagen.
