RJMPDRN® REC (DNA ya Sodium): Amakuru y'ubuvuzi y'iminsi 14-28 yemeza ko gusana, gukomeza no kurwanya iminkanyari bikora neza

Mu myaka ibarirwa muri za mirongo, PDRN yishingikirizaga ku gukuramo utunyangingo tw’imyororokere twa salmon, ishyiraho imbogamizi mu kudahindagurika kw’ibikomoka ku bimera, uburyo ADN ikurikirana ibintu bitandukanye, no kugenzura ubuziranenge bw’ibimera.

RJMPDRN® REC yacu (PDRN ya mbere ku isi ihuza ibinyabutabire)iratsinda izi mbogamizi binyuze mu buhanga buhanitse bw’ibinyabuzima. Iyi mpinduka idafite aho ikomoka ku nyamaswa kandi yubakiye ku buhanga bugenzurwa, ikoresha ikoranabuhanga rya biosynthesis. Imiterere yihariye ya PDRN ishyirwamo binyuze mu buryo bwa recombinant vectors kandi igakorwa binyuze mu gushyushya mikorobe. Ibi bikuraho kwishingikiriza ku bikoresho bikomoka ku mafi mu gihe bireba ko bihuye n’amahame agenga EU, Amerika, n’isi yose. Iki gicuruzwa gikomeza kuba gishingiye kuri ADN, ari umwimerere w’ibinyabuzima, kandi kidafite imboga.

Bitandukanye na PDRN isanzwe (iboneka binyuze mu gukuramo ADN idatoranyije), ikoranabuhanga rya recombinant rituma habaho kugenzura byimazeyo uruhererekane rwa ADN n'uburebure bw'ibice. Uruhererekane rw'imigozi migufi rugamije kurwanya ububyimbirwe; uruhererekane rw'imigozi hagati na kure rutuma uruhu ruvugururwa neza kandi rugasanwa. Uburyo bwo kwaguka mu nganda bugerwaho binyuze mu guhindura ubushyuhe n'ihungabana, ikoranabuhanga ryo gutegura uturemangingo neza cyane no gutunganya intambwe nyinshi, buri gihe bigatanga ubuziranenge bw'ibipimo by'ubuvuzi (≥99.5%).

Inyigo y'iminsi 28 ku bijyanye n'imikorere y'umubiri w'umuntu yakozwe ku bantu 31 hakoreshejwe umuti w'amazi wa RJMPDRN® REC wa 0.1%.

Ibisubizo byo ku munsi wa 14 (mu mubiri):
TEWL ↓9.58% (p<0.001)
Uburebure (R2) ↑19.33% (p<0.001)
Ubukomere (F4) ↓13.16% (p<0.001)
Igipimo cya erithema ↓7.11% (p<0.001)
Umubare w'iminkanyari ↓40.00% (p<0.001)
Agace k'iminkanyari ↓6.97% (p<0.001)
Uburebure bw'iminkanyari ↓8.14% (p=0.005)

Ibisubizo byo ku munsi wa 28 (mu mubiri):
TEWL ↓17.37% (p<0.001)
Uburebure (R2) ↑30.11% (p<0.001)
Ubukomere (F4) ↓19.83% (p<0.001)
Igipimo cya erithema ↓12.40% (p<0.001)
Umubare w'iminkanyari ↓46.67% (p<0.001)
Agace k'iminkanyari ↓7.44% (p<0.001)
Uburebure bw'iminkanyari ↓11.44% (p=0.002)

RJMPDRN® REC (PDRN ya mbere ku isi ihuza ibinyabutabire)Itanga uburyo bumwe bwo gusana no kuvugurura uruhu nk'uko PDRN isanzwe ibikora, ariko ifite uburyo bwo kubikora neza, ikoresha ibiribwa bitari ibyatsi, kandi ikaba ifite umutekano mu by'amategeko. Ni iterambere ry'ikoranabuhanga - ntabwo ari ikintu gisimbura gusa.